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home | fbf | awards 1997

France-Berkeley Fund

Grants Awarded in 1997

Mina J. Bissell, Ph.D. Director of Life Science Division, Lawrence Berkeley National Lab
Edmond Puvion, Ph.D. Director of the "Molecular Genetics and Integration of Molecular
Function" Unit, Institut de Recherche Sur le Cancer, Villejuif

"Regulation of Gene Expression by Nuclear architectural organization: an Ultrastructural Analysis Combining a Unique 3-Dimensional Cell Culture System with Novel Electron Microscopy Techniques". The Project hopes to establish the bases to study the dynamics of nuclear matrix and chromatin inter-relationships in differentiated and related tumor cells. Their goal is to develop, via this initial collaboration, a multi disciplinary research on the relationship between cell-bioarchitecture and gene regulation.



Professor Robert Brayton, EECS Dept., CAD Group, University of California, Berkeley
Professor Dominique Borrione, Laboratoire TIMA, Université Joseph Fourier, Grenoble

"Multi-Standard Verification Environment for Digital Systems Design." The VIS system of UC Berkeley uses the Verilog standard as an input description language, and the PREVAIL system of TIMA uses the VHDL standard. Both systems integrate CAD tools for the verification, diagnosis and synthesis of digital hardware. The project will implement a link between the two systems, to constitute as a whole a distributed, multi-standard comprehensive environment for digital systems design.



Professor Thomas Broadhurst, Dept. of Astronomy, University of California, Berkeley
James Bartlett, Astronome-adjoint, Observatoire de Strasbourg, Strasbourg

"Large-Scale Structure and Galaxy Formation", The principal problem in cosmology currently concerns the development of a detailed model for the formation of galaxies and large-scale structure in the Universe. The FBF funds will provide seed money necessary to finance a workshop and exchange visits to begin to develop the new research techniques and tools that will be essential to the interpretation of the impending flood of new observational data in cosmology.



Professor Lawrence Cohen, Dept. of Anthropology, University of California, Berkeley.
Marc Abeles, Directeur du Laboratoire d'Anthropologie des Institutions et Des Organizations, Paris

"Anthropological Concepts at the Turn of the Century: A French American Dialogue." The FBF grant will be used to help sponsor a conference which has two aims. The first is that of articulating and discussing the programmatic, methodological, and conceptual difference between two national traditions of anthropological research that have drifted increasingly far apart since the 1970s. The second and primary aim is that of identifying and exploring the theoretical and empirical common ground upon which the two traditions might build a more productive and more collaborative relationship in the coming century.



Dr. William Danchi, Space Sciences Laboratory, University of California, Berkeley
Dr. Jean Gay, Observatoire de la Cote d'Azur, Nice

"High Angular Resolution and Mass Loss of Evolved Stars". High angular resolution astronomy at infrared wavelengths holds great promise for solving fundamental astronomical problems from that of diameter of stars, to mass loss around stars, and the formation, evolution, and detection of planets. This proposal aims to further develop a collaboration between U.S. and French astronomers working with the U. C. Berkeley Infrared Spatial Interferometer, the forefront instrument at mid-infrared wavelengths. It will also seed new efforts to develop interferometry in the infrared.



Prof. Ralph Freeman, School of Optometry, University of California, Berkeley
Prof. Yves Fregnac, Institut Alfred Fessard, Gif-sur-Yvette

"Integrative Regulation of Functional Connectivity in the Developing and Adult Visual Cortex". The aim of this proposal is to study dynamic aspects of adaptative changes in functional connectivity of the visual system at the level of the visual cortex. These changes may be expressed in cortical networks during development and possibly during learning. The linking point of our proposal is that similar cellular mechanisms could be implicated on different time scales in the regulation of functional connectivity. At the integrative physiology level, we well use complementary electrophysiological and pharmacological techniques, and modeling tools, in order to compare adaptive processes in cortical circuits put into play during the natural development of cortical specificity and connectivity, versus those triggered during forced regimes of pre- and post synaptic correlations.



Dr. Melvin Klein, Structural Biology Division, Lawrence Berkeley National Lab.
Dr. Jean-Jacques Girerd, Institut de Chimie Moleculaire D'Orsay, Orsay

"XAS (xanes and exafs) studies coupled to electro-chemistry of chemical models of the catalyticsite of the oxygene evolving center of PSII".



Prof. Paolo Mancosu, Dept. of Philosophy, University of California, Berkeley
Prof. Hourya Sinaceur, Institut d'Histoire et Philosophie des Sciences et des Techniques, Paris

"Bernard Bolzano: Philosophy of Logic and Mathematics". A workshop on Bolzano's work in philosophy of logic and mathematics with emphasis on the relevance of Bolzano's work to contemporary philosophical projects.



Prof. Frank McLarnon, Lawrence National Laboratory, Berkeley
Prof. Françoise Argoul, Centre de Recherche Paul Pascal, Pessac

"Application of advanced optical techniques for probing interfacial electrochemical processes". The purpose of this scientific project between the Centre de Recherche Paul Pascal and the Lawrence Berkeley Laboratory is the sharing of our respective expertise in the application of optical methods for in-situ probing of interfacial phenomenon. In particular the techniques which are of principal interest are respectively: spectroscopic and time resolved ellipsometry, attenuated total reflectance (ATR) applied to the characterization of transport in the neighborhood of an electrochemical interface and Raman spectroscopy.



Dr. Saul Perlmutter, Center for Particle Astrophysics, Lawrence Berkeley National Laboratory
Dr. Pain Reynald, Laboratoire de Physique Nucleaire de la Haute Energie, Paris

"Measurement of the cosmological parameters using type Ia supermovae". The collaboration of the two groups will make it possible to obtain a new measurement of Omega m using type Ia supernovae. This measurement will be obtained using a population of more distant type Ia Sne and will therefore end up having a better precision than previous measurements.



Prof. Richard Saykally, Dept. of Chemistry, University of California , Berkeley
Prof. Claude Leforestier, Lab. Structure et Dynamique des Systemes Moleculaires et Solides, Montpellier

"The Dynamics of Nucleotide Base Hydration". The hydration of nucleotide bases is a process of fundamental significance in numerous biological contexts, e.g., replication, transcription, mutations. We propose to study the dynamics of nucleotide base-water interactions using complementary experimental and theoretical approaches.



Prof. David Stronach, Dept. of Near Eastern Studies, University of California, Berkeley
Dr. Frantz Grenet, Centre d'Archéologie, Ecole Normale Supérieure, Paris

Workshop on strategies for joint archaeological excavation and research in Central Asia and for the development of curricula connected with Central Asian Studies.



Prof. Brian Staskawicz, Dept. of Plant Biology, Berkeley
Dr. Ulla Bonas, CNRS-Institut des Sciences Végétales, Gif-sur-Yvette

"Identification and characterization of novel genes for disease resistance in Capsicum annum". A collaborative effort to identify plant genes controlling disease resistance will be undertaken in both Gif and Berkeley. Fast-neutron mutagenized seed will be screened to identify disease susceptible plant mutant that will assist in cloning the corresponding wild type genes. This will lead to the identification and characterization of novel genes involved in signal perception and signal transduction pathways that control plant disease resistance. In addition, the two laboratories will share DNA libraries and technology to identify and clone the pepper Bs3 gene.



Prof. Michael Watts, Institute of International Studies, Berkeley
Prof. Gilles Allaire, INRA, Economie Sociologie Rurales, Castanet-Tolosan

"Systems and Trajectories of Innovation: Institutions, Technology and Conventions in Agriculture Regulation (French-American comparisons). This project entails a Workshop bringing together French and American researchers working on (sectoral) innovation in agriculture focusing on theoretical and conceptual questions of decentralization/privatization, quality institutional and political contests of regulation and biotechnology.

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